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A lysosomal switch triggers proteostasis renewal in the immortal C. elegans germ lineage (vol 551, pg 629, 2017) 期刊论文
NATURE, 2020, 580 (7802) : E5-E5
作者:  Lu, Zhihao;  Zou, Jianling;  Li, Shuang;  Topper, Michael J.;  Tao, Yong;  Zhang, Hao;  Jiao, Xi;  Xie, Wenbing;  Kong, Xiangqian;  Vaz, Michelle;  Li, Huili;  Cai, Yi;  Xia, Limin;  Huang, Peng;  Rodgers, Kristen;  Lee, Beverly;  Riemer, Joanne B.;  Day, Chi-Ping;  Yen, Ray-Whay Chiu;  Cui, Ying;  Wang, Yujiao;  Wang, Yanni;  Zhang, Weiqiang;  Easwaran, Hariharan;  Hulbert, Alicia;  Kim, KiBem;  Juergens, Rosalyn A.;  Yang, Stephen C.;  Battafarano, Richard J.;  Bush, Errol L.;  Broderick, Stephen R.;  Cattaneo, Stephen M.;  Brahmer, Julie R.;  Rudin, Charles M.;  Wrangle, John;  Mei, Yuping;  Kim, Young J.;  Zhang, Bin;  Wang, Ken Kang-Hsin;  Forde, Patrick M.;  Margolick, Joseph B.;  Nelkin, Barry D.;  Zahnow, Cynthia A.;  Pardoll, Drew M.;  Housseau, Franck;  Baylin, Stephen B.;  Shen, Lin;  Brock, Malcolm V.
收藏  |  浏览/下载:50/0  |  提交时间:2020/07/03
Nightside condensation of iron in an ultrahot giant exoplanet 期刊论文
NATURE, 2020, 580 (7805) : 597-+
作者:  Lu, Zhihao;  Zou, Jianling;  Li, Shuang;  Topper, Michael J.;  Tao, Yong;  Zhang, Hao;  Jiao, Xi;  Xie, Wenbing;  Kong, Xiangqian;  Vaz, Michelle;  Li, Huili;  Cai, Yi;  Xia, Limin;  Huang, Peng;  Rodgers, Kristen;  Lee, Beverly;  Riemer, Joanne B.;  Day, Chi-Ping;  Yen, Ray-Whay Chiu;  Cui, Ying;  Wang, Yujiao;  Wang, Yanni;  Zhang, Weiqiang;  Easwaran, Hariharan;  Hulbert, Alicia;  Kim, KiBem;  Juergens, Rosalyn A.;  Yang, Stephen C.;  Battafarano, Richard J.;  Bush, Errol L.;  Broderick, Stephen R.;  Cattaneo, Stephen M.;  Brahmer, Julie R.;  Rudin, Charles M.;  Wrangle, John;  Mei, Yuping;  Kim, Young J.;  Zhang, Bin;  Wang, Ken Kang-Hsin;  Forde, Patrick M.;  Margolick, Joseph B.;  Nelkin, Barry D.;  Zahnow, Cynthia A.;  Pardoll, Drew M.;  Housseau, Franck;  Baylin, Stephen B.;  Shen, Lin;  Brock, Malcolm V.
收藏  |  浏览/下载:95/0  |  提交时间:2020/07/03

Ultrahot giant exoplanets receive thousands of times Earth'  s insolation(1,2). Their high-temperature atmospheres (greater than 2,000 kelvin) are ideal laboratories for studying extreme planetary climates and chemistry(3-5). Daysides are predicted to be cloud-free, dominated by atomic species(6) and much hotter than nightsides(5,7,8). Atoms are expected to recombine into molecules over the nightside(9), resulting in different day and night chemistries. Although metallic elements and a large temperature contrast have been observed(10-14), no chemical gradient has been measured across the surface of such an exoplanet. Different atmospheric chemistry between the day-to-night ('  evening'  ) and night-to-day ('  morning'  ) terminators could, however, be revealed as an asymmetric absorption signature during transit(4,7,15). Here we report the detection of an asymmetric atmospheric signature in the ultrahot exoplanet WASP-76b. We spectrally and temporally resolve this signature using a combination of high-dispersion spectroscopy with a large photon-collecting area. The absorption signal, attributed to neutral iron, is blueshifted by -11 +/- 0.7 kilometres per second on the trailing limb, which can be explained by a combination of planetary rotation and wind blowing from the hot dayside(16). In contrast, no signal arises from the nightside close to the morning terminator, showing that atomic iron is not absorbing starlight there. We conclude that iron must therefore condense during its journey across the nightside.


Absorption lines of iron in the dayside atmosphere of an ultrahot giant exoplanet disappear after travelling across the nightside, showing that the iron has condensed during its travel.


  
Passenger hotspot mutations in cancer driven by APOBEC3A and mesoscale genomic features 期刊论文
SCIENCE, 2019, 364 (6447) : 1251-+
作者:  Buisson, Remi;  Langenbucher, Adam;  Bowen, Danae;  Kwan, Eugene E.;  Benes, Cyril H.;  Zou, Lee;  Lawrence, Michael S.
收藏  |  浏览/下载:9/0  |  提交时间:2019/11/27
Racial profiling harms science 期刊论文
SCIENCE, 2019, 363 (6433) : 1290-1291
作者:  Lu, Shan;  Han, Zhe;  Hung, Mien-Chie;  Xu, Jianming;  Xu, Yong;  Zheng, Pan;  Zheng, Zhi-Ming;  Zou, Lee;  Li, Zihai;  Zheng, Lei;  Kang, Yibin;  Yang, Yingzi;  He, Lin;  Liao, X. Charlene;  Yu, Hongtao;  Yue, Zhenyu;  Liu, Shan-Lu;  Zheng, Hui
收藏  |  浏览/下载:21/0  |  提交时间:2019/11/27
A mitosis-specific and R loop-driven ATR pathway promotes faithful chromosome segregation 期刊论文
SCIENCE, 2018, 359 (6371) : 108-113
作者:  Kabeche, Lilian;  Nguyen, Hai Dang;  Buisson, Remi;  Zou, Lee
收藏  |  浏览/下载:15/0  |  提交时间:2019/11/27
RNA m(6)A methylation regulates the ultraviolet-induced DNA damage response (vol 543, pg 573, 2017) 期刊论文
NATURE, 2017, 552 (7685) : 430-430
作者:  Xiang, Yang;  Laurent, Benoit;  Hsu, Chih-Hung;  Nachtergaele, Sigrid;  Lu, Zhike;  Sheng, Wanqiang;  Xu, Chuanyun;  Chen, Hao;  Ouyang, Jian;  Wang, Siqing;  Ling, Dominic;  Hsu, Pang-Hung;  Zou, Lee;  Jambhekar, Ashwini;  He, Chuan;  Shi, Yang
收藏  |  浏览/下载:24/0  |  提交时间:2019/11/27
Assessment of carbonaceous aerosols in Shanghai, China - Part 1: long-term evolution, seasonal variations, and meteorological effects 期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2017, 17 (16)
作者:  Chang, Yunhua;  Deng, Congrui;  Cao, Fang;  Cao, Chang;  Zou, Zhong;  Liu, Shoudong;  Lee, Xuhui;  Li, Jun;  Zhang, Gan;  Zhang, Yanlin
收藏  |  浏览/下载:13/0  |  提交时间:2019/04/09