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Retrospect driving forces and forecasting reduction potentials of energy-related industrial carbon emissions from China's manufacturing at city level 期刊论文
ENVIRONMENTAL RESEARCH LETTERS, 2020, 15 (7)
作者:  Su, Yongxian;  Wang, Yilong;  Zheng, Bo;  Ciais, Philippe;  Wu, Jianping;  Chen, Xiuzhi;  Wang, Yang;  Wang, Changjian;  Ye, Yuyao;  Li, Qian;  Zhang, Chaoqun;  Zhang, Hongou;  Huang, Guangqing;  Huang, Ningsheng;  Lafortezza, Raffaele
收藏  |  浏览/下载:45/0  |  提交时间:2020/08/18
carbon emission mitigation  city level  manufacturing  scenario design  carbon emission driver  mitigation strategy  
Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor 期刊论文
NATURE, 2020, 581 (7807) : 215-+
作者:  Goudeau, Jerome;  Samaddar, Madhuja;  Bohnert, K. Adam;  Kenyon, Cynthia
收藏  |  浏览/下载:39/0  |  提交时间:2020/07/03

A new and highly pathogenic coronavirus (severe acute respiratory syndrome coronavirus-2, SARS-CoV-2) caused an outbreak in Wuhan city, Hubei province, China, starting from December 2019 that quickly spread nationwide and to other countries around the world(1-3). Here, to better understand the initial step of infection at an atomic level, we determined the crystal structure of the receptor-binding domain (RBD) of the spike protein of SARS-CoV-2 bound to the cell receptor ACE2. The overall ACE2-binding mode of the SARS-CoV-2 RBD is nearly identical to that of the SARS-CoV RBD, which also uses ACE2 as the cell receptor(4). Structural analysis identified residues in the SARS-CoV-2 RBD that are essential for ACE2 binding, the majority of which either are highly conserved or share similar side chain properties with those in the SARS-CoV RBD. Such similarity in structure and sequence strongly indicate convergent evolution between the SARS-CoV-2 and SARS-CoV RBDs for improved binding to ACE2, although SARS-CoV-2 does not cluster within SARS and SARS-related coronaviruses(1-3,5). The epitopes of two SARS-CoV antibodies that target the RBD are also analysed for binding to the SARS-CoV-2 RBD, providing insights into the future identification of cross-reactive antibodies.


  
Impact of climate change on New York City's coastal flood hazard: Increasing flood heights from the preindustrial to 2300 CE 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017, 114 (45) : 11861-11866
作者:  Garner, Andra J.;  Mann, Michael E.;  Emanuel, Kerry A.;  Kopp, Robert E.;  Lin, Ning;  Alley, Richard B.;  Horton, Benjamin P.;  DeConto, Robert M.;  Donnelly, Jeffrey P.;  Pollard, David
收藏  |  浏览/下载:26/0  |  提交时间:2019/11/27
tropical cyclones  flood height  New York City  sea-level rise  coastal flooding  
The environmental consequences of domestic and foreign investment: Evidence from China 期刊论文
ENERGY POLICY, 2017, 108
作者:  Liu, Yiming;  Hao, Yu;  Gao, Yixuan
收藏  |  浏览/下载:20/0  |  提交时间:2019/04/09
Fixed asset investment (FAI)  Foreign direct investment (FDI)  Environmental quality  City-level panel data  Spatial correlation