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VDAC oligomers form mitochondrial pores to release mtDNA fragments and promote lupus-like disease 期刊论文
SCIENCE, 2019, 366 (6472) : 1531-+
作者:  Kim, Jeonghan;  Gupta, Rajeev;  Blanco, Luz P.;  Yang, Shutong;  Shteinfer-Kuzmine, Anna;  Wang, Kening;  Zhu, Jun;  Yoon, Hee Eun;  Wang, Xinghao;  Kerkhofs, Martijn;  Kang, Hyeog;  Brown, Alexandra L.;  Park, Sung-Jun;  Xu, Xihui;  van Rilland, Eddy Zandee;  Kim, Myung K.;  Cohen, Jeffrey I.;  Kaplan, Mariana J.;  Shoshan-Barmatz, Varda;  Chung, Jay H.
收藏  |  浏览/下载:14/0  |  提交时间:2020/02/17
Foldamer-templated catalysis of macrocycle formation 期刊论文
SCIENCE, 2019, 366 (6472) : 1528-+
作者:  Girvin, Zebediah C.;  Andrews, Mary Katherine;  Liu, Xinyu;  Gellman, Samuel H.
收藏  |  浏览/下载:7/0  |  提交时间:2020/02/17
Comprehensive AAV capsid fitness landscape reveals a viral gene and enables machine-guided design 期刊论文
SCIENCE, 2019, 366 (6469) : 1139-+
作者:  Ogden, Pierce J.;  Kelsic, Eric D.;  Sinai, Sam;  Church, George M.
收藏  |  浏览/下载:9/0  |  提交时间:2020/02/17
SEEING FOSSILS IN A NEW LIGHT 期刊论文
SCIENCE, 2019, 366 (6462) : 176-178
作者:  Vogel, Gretchen
收藏  |  浏览/下载:0/0  |  提交时间:2019/11/27
Structure of the Cdc48 segregase in the act of unfolding an authentic substrate 期刊论文
SCIENCE, 2019, 365 (6452) : 502-+
作者:  Cooney, Ian;  Han, Han;  Stewart, Michael G.;  Carson, Richard H.;  Hansen, Daniel T.;  Iwasa, Janet H.;  Price, John C.;  Hill, Christopher P.;  Shen, Peter S.
收藏  |  浏览/下载:7/0  |  提交时间:2019/11/27
A cytosine deaminase for programmable single-base RNA editing 期刊论文
SCIENCE, 2019, 365 (6451) : 382-+
作者:  Abudayyeh, Omar O.;  Gootenberg, Jonathan S.;  Franklin, Brian;  Koob, Jeremy;  Kellner, Max J.;  Ladha, Alim;  Joung, Julia;  Kirchgatterer, Paul;  Cox, David B. T.;  Zhang, Feng
收藏  |  浏览/下载:11/0  |  提交时间:2019/11/27
De novo design of tunable, pH-driven conformational changes 期刊论文
SCIENCE, 2019, 364 (6441) : 658-+
作者:  Boyken, Scott E.;  Benhaim, Mark A.;  Busch, Florian;  Jia, Mengxuan;  Bick, Matthew J.;  Choi, Heejun;  Klima, Jason C.;  Chen, Zibo;  Walkey, Carl;  Mileant, Alexander;  Sahasrabuddhe, Aniruddha;  Wei, Kathy Y.;  Hodge, Edgar A.;  Byron, Sarah;  Quijano-Rubio, Alfredo;  Sankaran, Banumathi;  King, Neil P.;  Lippincott-Schwartz, Jennifer;  Wysocki, Vicki H.;  Lee, Kelly K.;  Baker, David
收藏  |  浏览/下载:17/0  |  提交时间:2019/11/27
VACCINOLOGY Structural topology defines protective CD8(+) T cell epitopes in the HIV proteome 期刊论文
SCIENCE, 2019, 364 (6439) : 480-+
作者:  Gaiha, Gaurav D.;  Rossin, Elizabeth J.;  Urbach, Jonathan;  Landeros, Christian;  Collins, David R.;  Nwonu, Chioma;  Muzhingi, Itai;  Anahtar, Melis N.;  Waring, Olivia M.;  Piechocka-Trocha, Alicja;  Waring, Michael;  Worrall, Daniel P.;  Ghebremichael, Musie S.;  Newman, Ruchi M.;  Power, Karen A.;  Allen, Todd M.;  Chodosh, James;  Walker, Bruce D.
收藏  |  浏览/下载:10/0  |  提交时间:2019/11/27
Packing of apolar side chains enables accurate design of highly stable membrane proteins 期刊论文
SCIENCE, 2019, 363 (6434) : 1418-+
作者:  Mravic, Marco;  Thomaston, Jessica L.;  Tucker, Maxwell;  Solomon, Paige E.;  Liu, Lijun;  DeGrado, William F.
收藏  |  浏览/下载:7/0  |  提交时间:2019/11/27
Molecular basis for pore blockade of human Na+ channel Na(v)1.2 by the mu-conotoxin KIIIA 期刊论文
SCIENCE, 2019, 363 (6433) : 1309-+
作者:  Pan, Xiaojing;  Li, Zhangqiang;  Huang, Xiaoshuang;  Huang, Gaoxingyu;  Gao, Shuai;  Shen, Huaizong;  Liu, Lei;  Lei, Jianlin;  Yan, Nieng
收藏  |  浏览/下载:6/0  |  提交时间:2019/11/27